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Sermorelin

CAS #: 86168-78-7
Research Use Only

Supplied strictly for in-vitro and laboratory research. Not for human or veterinary use. By ordering, you confirm you are a qualified researcher handling these materials per applicable regulations and safe lab practice.

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Format
Purchase Type
Sermorelin
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$49.00
One-time
5mg
Certificate of Analysis
Third-party tested for purity, ID, and quantity.

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Sermorelin Overview

Sermorelin is a synthetic analog of the first 29 amino acids of growth-hormone-releasing hormone, the portion that carries its biological activity. It is studied for its ability to stimulate endogenous growth-hormone release and is a frequent tool in endocrine and somatotropic-axis research, including work on pituitary reserve.

History

Researchers identified the N-terminal 29-residue segment as the active core of GHRH, and sermorelin (GRF 1-29) was synthesized to reproduce it. Because it triggers the body's own growth-hormone machinery rather than replacing the hormone, it was characterized as both a research probe and a diagnostic tool for assessing pituitary GH reserve and somatotropic signaling.

Sermorelin Structure

CAS #: 86168-78-7
Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
MW: 3357.93 g/mol
PubChem ID: 16132413

Research Findings

Sermorelin has been examined in endocrine models for GHRH-receptor binding, growth-hormone-pulse stimulation, and IGF-1 axis dynamics. Because it works through the native GHRH receptor, sermorelin lets researchers study growth-hormone release in a form that preserves the axis's own pulsatile control rather than overriding it. That property is what keeps it useful for characterizing pituitary responsiveness and somatotropic signaling in laboratory settings.

Key Areas of Research:
  • Endocrine: GHRH-receptor agonism, GH secretion
  • Metabolic: IGF-1 axis, body-composition signaling
  • Systemic: Pituitary reserve, pulsatile dynamics

References

  • Prakash A. & Goa KL. (1999). Review of a GHRH(1-29) analog.
  • Walker RF. et al. (1990). GH-releasing activity in experimental models.
  • Corpas E. et al. (1993). GHRH-fragment effects on the somatotropic axis.
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Precision Lyophilization

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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water, sterile syringes, and appropriate research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
Sermorelin
$49.00