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PT-141

CAS #: 189691-06-3
Research Use Only

Supplied strictly for in-vitro and laboratory research. Not for human or veterinary use. By ordering, you confirm you are a qualified researcher handling these materials per applicable regulations and safe lab practice.

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PT-141
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PT-141 Overview

PT-141, also known as bremelanotide, is a melanocortin-receptor agonist derived from Melanotan II. It is investigated in research examining central nervous-system signaling pathways, with a focus on melanocortin-mediated activity in the brain.

History

Developed by Palatin Technologies following observations made during Melanotan II research, PT-141 differs from its predecessor by carrying a carboxyl group in place of an amide. It was investigated through clinical programs centered on melanocortin-mediated arousal signaling, positioning it as a more targeted successor within the melanocortin class.

PT-141 Structure

CAS #: 189691-06-3
Formula: C₅₀H₆₈N₁₄O₁₀
MW: 1025.16 g/mol
PubChem ID: 9941379

Research Findings

PT-141 has been examined in receptor-pharmacology and behavioral models for MC3R and MC4R agonism and central melanocortin-pathway signaling. Compared with its structural parent, PT-141 shifts the research focus toward central melanocortin signaling rather than pigmentation, which is what distinguishes its profile. Its narrower receptor emphasis makes it a useful tool for studying MC3R and MC4R activity in the central nervous system.

Key Areas of Research:
  • Signaling: Melanocortin-receptor agonism (MC3R/MC4R)
  • Neurological: Central arousal pathways
  • Systemic: Melanocortin-pathway dynamics

References

  • Wessells H. et al. (2000). Melanocortin-analog signaling in experimental models.
  • Diamond LE. et al. (2004). Central melanocortin-agonist characterization.
  • Clayton AH. et al. (2016). Melanocortin-agonist clinical evaluation (RECONNECT).
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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water, sterile syringes, and appropriate research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
PT-141
$49.00