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For laboratory research use only · Not for human consumption · Read handling terms →
Third-party HPLC, mass-spec, and endotoxin testing on every batch — with the Certificate of Analysis included, not on request.
Nicotinamide adenine dinucleotide is an essential coenzyme at the center of cellular energy metabolism and redox reactions. Research explores its role in mitochondrial function, DNA-repair signaling, and sirtuin-dependent pathways, where it acts both as an electron carrier and as a substrate consumed by signaling enzymes.
First described in the early 20th century under the name "cozymase," NAD+ has been a cornerstone of biochemistry for more than a hundred years. Renewed research interest has shifted toward how it is synthesized, how its levels decline with age, and its function as a substrate for enzymes such as sirtuins and PARPs, moving it from a classical metabolic cofactor to an active subject in aging and signaling research.
NAD+ has been studied across metabolic and cellular models for redox cycling, sirtuin- and PARP-dependent signaling, mitochondrial function, and energy-homeostasis pathways. Its dual role, cycling as a redox carrier while also being consumed by signaling enzymes, is what makes it a recurring focus in both bioenergetics and aging research. As one of the most fundamental cofactors in the cell, it serves as a central reference molecule for studying energy homeostasis and enzyme-driven signaling.
Same-day dispatch before 2:00 PM CST, Monday through Saturday. Store lyophilized vials at −20°C, protected from light; reconstituted solutions at 2–8°C. Discreet, temperature-safe packaging. Guaranteed delivery with free reshipment.
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