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NAD+

CAS #: 53-84-9
Research Use Only

Supplied strictly for in-vitro and laboratory research. Not for human or veterinary use. By ordering, you confirm you are a qualified researcher handling these materials per applicable regulations and safe lab practice.

Size
Format
Purchase Type
NAD+
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$79.00
One-time
500mg
Certificate of Analysis
Third-party tested for purity, ID, and quantity.

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NAD+ Overview

Nicotinamide adenine dinucleotide is an essential coenzyme at the center of cellular energy metabolism and redox reactions. Research explores its role in mitochondrial function, DNA-repair signaling, and sirtuin-dependent pathways, where it acts both as an electron carrier and as a substrate consumed by signaling enzymes.

History

First described in the early 20th century under the name "cozymase," NAD+ has been a cornerstone of biochemistry for more than a hundred years. Renewed research interest has shifted toward how it is synthesized, how its levels decline with age, and its function as a substrate for enzymes such as sirtuins and PARPs, moving it from a classical metabolic cofactor to an active subject in aging and signaling research.

NAD+ Structure

CAS #: 53-84-9
Formula: C₂₁H₂₇N₇O₁₄P₂
MW: 663.43 g/mol
PubChem ID: 5892

Research Findings

NAD+ has been studied across metabolic and cellular models for redox cycling, sirtuin- and PARP-dependent signaling, mitochondrial function, and energy-homeostasis pathways. Its dual role, cycling as a redox carrier while also being consumed by signaling enzymes, is what makes it a recurring focus in both bioenergetics and aging research. As one of the most fundamental cofactors in the cell, it serves as a central reference molecule for studying energy homeostasis and enzyme-driven signaling.

Key Areas of Research:
  • Metabolic: Redox balance, energy metabolism
  • Signaling: Sirtuin and PARP activity
  • Systemic: Mitochondrial function, aging-related pathways

References

  • Verdin E. (2015). NAD+ in aging and metabolic signaling.
  • Rajman L. et al. (2018). NAD+ biology and precursor research.
  • Yoshino J. et al. (2018). NAD+ intermediates in metabolic models.
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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water, sterile syringes, and appropriate research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
NAD+
$79.00