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Fast Track Labs

MOTS-c

CAS #: 1627580-64-6
Research Use Only

Supplied strictly for in-vitro and laboratory research. Not for human or veterinary use. By ordering, you confirm you are a qualified researcher handling these materials per applicable regulations and safe lab practice.

Size
Format
Purchase Type
MOTS-c
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$49.00
One-time
10mg
Certificate of Analysis
Third-party tested for purity, ID, and quantity.

Customers can verify COA's here: https://horizonanalytical.com/verify-coa

MOTS-c Overview

MOTS-c is a mitochondrial-derived peptide studied for its role in metabolic regulation and the cellular stress response. Research focuses on its influence on insulin sensitivity, AMPK signaling, and mitochondrial homeostasis, placing it among a distinct class of peptides encoded within the mitochondrial genome rather than the nucleus.

History

Identified in the mid-2010s as a mitochondrial-encoded regulator, MOTS-c was characterized as a mitokine, a signal originating in the mitochondria that translocates to the nucleus and influences adaptive gene expression. Later work examined its involvement in exercise responses and metabolic stress, expanding interest in mitochondrial-to-nuclear communication.

MOTS-c Structure

CAS #: 1627580-64-6
Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
MW: 2174.62 g/mol
PubChem ID: 146675088

Research Findings

MOTS-c has been examined in metabolic models for AMPK-pathway activation, glucose handling, insulin-sensitivity signaling, and exercise-associated adaptation. Its identity as a mitokine is the central research theme, since it offers a model for how mitochondria signal metabolic state to the rest of the cell. That makes MOTS-c a useful tool for studying the intersection of energy metabolism, stress adaptation, and gene regulation in the laboratory.

Key Areas of Research:
  • →Metabolic: AMPK signaling, glucose regulation
  • →Mitochondrial: Mitokine dynamics, nuclear gene expression
  • →Systemic: Physical-capacity and aging-related pathways

References

  • Lee C. et al. (2015). Characterization of a mitochondrial-derived metabolic peptide.
  • Reynolds JC. et al. (2021). Exercise-associated regulator of metabolic homeostasis.
  • Kim KH. et al. (2018). Mitochondrial-peptide signaling in metabolic stress.

Our Process

STEP 01
Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 02
Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 03
Same-Day Fulfillment

Orders dispatched same-day from our U.S. facility.

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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water, sterile syringes, and appropriate research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
MOTS-c
$49.00