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Products/KPV
Anti-Inflammatory

KPV

99.3%+ · COA VerifiedIn stock
CAS 67727-97-3 · For laboratory research use only
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HPLC Purity99.3%
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Third-party HPLC, mass-spec, and endotoxin testing on every batch — with the Certificate of Analysis included, not on request.

99.3%+ verified purity HPLC + Mass Spec Endotoxin tested
Overview+

KPV is a tripeptide fragment derived from alpha-MSH, studied for its role in modulating inflammatory signaling pathways. Research interest includes its activity in gut and immune-response models, where it appears to retain the anti-inflammatory character of its parent hormone in a much smaller molecule.

History+

Identified as the active C-terminal fragment of alpha-MSH, KPV was characterized in models of inflammation, where it kept the anti-inflammatory properties of the full hormone without the pigmentary activity associated with the parent molecule. That separation of activities is what made the short fragment an attractive research tool.

Structure & specifications+
CAS #: 67727-97-3
Formula: C₁₆H₃₀N₄O₄
MW: 342.44 g/mol
PubChem ID: 125672
Research findings+

KPV has been studied in immune and epithelial models for modulation of NF-kB signaling, pro-inflammatory cytokine activity, and intestinal-inflammation pathways. The research value of KPV lies in isolating anti-inflammatory activity from the broader alpha-MSH molecule, which lets investigators study that signaling in a defined and compact form. It is used particularly in intestinal-inflammation models, where its effect on NF-kB and cytokine pathways can be examined directly.

Key areas of research
  • →Immune: Anti-inflammatory signaling, cytokine modulation
  • →Epithelial: Intestinal-barrier and inflammation models
  • →Systemic: NF-kB pathway dynamics
Shipping, storage & handling+

Same-day dispatch before 2:00 PM CST, Monday through Saturday. Store lyophilized vials at −20°C, protected from light; reconstituted solutions at 2–8°C. Discreet, temperature-safe packaging. Guaranteed delivery with free reshipment.

References+
  • Lipton JM. & Catania A. (1997). Anti-inflammatory activity of alpha-MSH peptides.
  • Dalmasso G. et al. (2008). KPV uptake and intestinal inflammation.
  • Kannengiesser K. et al. (2008). Tripeptide effects in colitis models.

What’s actually in your vial?

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Fast Track Labs
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Third-party COA (HPLC + Mass Spec)
✓Every batch, included
✕Rarely, or on request
Verified purity
✓99.3%+
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Endotoxin tested
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Frequently asked questions

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water and appropriate sterile research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours, Monday through Saturday. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
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Per vial
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