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Tesamorelin

CAS #: 901758-09-6
Research Use Only

Supplied strictly for in-vitro and laboratory research. Not for human or veterinary use. By ordering, you confirm you are a qualified researcher handling these materials per applicable regulations and safe lab practice.

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Tesamorelin
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$79.00
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Batch-specific Certificate of Analysis included with every shipment — third-party tested for 99.2% purity, ID, and quantity.

Tesamorelin Overview

Tesamorelin is a synthetic 44-amino-acid analog of growth-hormone-releasing hormone (GHRH), modified at the N-terminus to resist enzymatic breakdown and hold its activity in solution. In laboratory research it serves as a tool for probing the somatotropic axis, engaging the GHRH receptor to influence pulsatile growth-hormone signaling and downstream IGF-1 activity. Much of the experimental interest centers on how that signaling connects to lipid handling and visceral adipose behavior in controlled metabolic models.

History

Tesamorelin came out of work on stabilizing native GHRH, whose short circulating life limited its use as a research probe. Adding a trans-3-hexenoyl group to the N-terminal residue produced an analog resistant to dipeptidyl-peptidase cleavage while preserving receptor affinity. Through the 2000s it was characterized across clinical and preclinical models focused on the GH/IGF-1 axis and visceral fat distribution, and it has since stayed a reference compound for studying stabilized GHRH signaling.

Tesamorelin Structure

CAS #: 901758-09-6
Formula: C₂₂₁H₃₆₆N₇₂O₆₇S
MW: 5135.86 g/mol
PubChem ID: 16137828

Research Findings

Tesamorelin has been studied in endocrine and metabolic systems for GHRH-receptor agonism, growth-hormone secretion, IGF-1 modulation, and signaling tied to visceral adipose tissue. The work spans receptor-level pharmacology through to body-composition and hepatic-lipid endpoints in preclinical models. Taken together, these lines of work position tesamorelin as a stabilized probe for the growth-hormone axis, letting researchers separate GHRH-receptor engagement from the metabolic readouts that follow. Its resistance to enzymatic degradation makes it a durable tool for characterizing somatotropic signaling and adipose-related pathways in laboratory settings.

Key Areas of Research:
  • Endocrine: GHRH-receptor binding, pulsatile GH release
  • Metabolic: IGF-1 axis, visceral adipose dynamics
  • Systemic: Hepatic lipid handling, body-composition pathways

References

  • Falutz J. et al. (2007). GHRH-analog effects on visceral fat (randomized controlled trial).
  • Stanley TL. et al. (2014). Effects on the GH/IGF-1 axis and liver fat.
  • Grinspoon S. et al. (2010). Metabolic outcomes in lipodystrophy models.
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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water, sterile syringes, and appropriate research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
Tesamorelin
$79.00