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DP3-R

CAS #: 2381089-83-2
Research Use Only

Supplied strictly for in-vitro and laboratory research. Not for human or veterinary use. By ordering, you confirm you are a qualified researcher handling these materials per applicable regulations and safe lab practice.

Size
Format
Purchase Type
DP3-R
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$139.00
One-time
10mg
Certificate of Analysis
Third-party tested for purity, ID, and quantity.

Customers can verify COA's here: https://horizonanalytical.com/verify-coa

DP3-R Overview

DP3-R is a metabolic reference compound in the FastTrackLabs DP series, supplied for laboratory study of energy balance and metabolic signaling. Research interest centers on combined activity across three incretin and glucagon pathways and how that convergence affects appetite signaling, glucose handling, and energy expenditure in controlled models.

History

DP3-R was developed in the early 2020s as a first-in-class single-molecule triagonist acting at the GIP, GLP-1, and glucagon receptors. It entered clinical investigation for obesity and type-2-diabetes endpoints, building directly on the single- and dual-agonist classes that came before it and extending the multi-receptor design further.

DP3-R Structure

CAS #: 2381089-83-2
Formula: C₂₂₃H₃₄₃N₄₆O₇₀
MW: 4731.33 g/mol

Research Findings

DP3-R has been investigated in metabolic and endocrine models for combined GIP/GLP-1/glucagon-receptor activity affecting appetite signaling, glucose handling, and energy expenditure. The triagonist design is the defining research feature, since adding glucagon-receptor activity to the incretin pathways introduces an energy-expenditure component alongside appetite and glucose effects. As a reference triple agonist, DP3-R serves as the most complex comparator in the incretin-agonist class for laboratory metabolic research.

Key Areas of Research:
  • Metabolic: Glucose regulation, energy balance
  • Endocrine: Multi-incretin receptor signaling
  • Systemic: Appetite and weight-related pathways

References

  • Jastreboff AM. et al. (2023). Triple-agonist effects in an obesity model (phase 2).
  • Rosenstock J. et al. (2023). Triple-agonist effects on glycemic endpoints in type-2 diabetes.
  • Coskun T. et al. (2022). Pharmacology of a GIP/GLP-1/glucagon triagonist.
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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?+
Each vial contains the labeled mass of lyophilized peptide. Selected sizes appear above the price.
Are additional supplies needed?+
Reconstitution requires bacteriostatic water, sterile syringes, and appropriate research labware – not included.
How long does a vial last?+
Sealed lyophilized vials are stable at −20°C for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Does the product come with instructions?+
Each shipment includes the batch-specific Certificate of Analysis and recommended handling protocol.
What purity level is guaranteed?+
≥ 99% by reverse-phase HPLC (UV-220nm), confirmed via ESI-TOF mass spectrometry.
How should I store these products?+
Store sealed vials at −20°C, protected from light. Reconstituted solutions at 2–8°C.
What are peptides and how do they work?+
Peptides are short chains of amino acids that occur naturally in organisms, where they act as messengers in many biological systems. While some peptides have been developed for medical use, laboratory research focuses on understanding their activity at the cellular level, examining how they impact essential processes in vitro.
Do these products come with instructions?+
Products from Fast Track Labs are supplied without usage instructions, as they are designated solely for in vitro laboratory research and prohibited by law for human or animal consumption. Any misuse or unlawful application of these products will result in permanent denial of service.
How long do products take to deliver?+
Orders are typically processed and shipped within 24 hours on weekdays. Delivery times vary by location, but most domestic orders arrive within 3–5 business days. You'll receive tracking information as soon as your order ships.
DP3-R
$139.00